Severe stenosis generally refers to severe narrowing of the lumen of the coronary arteries, a phenomenon that can cause coronary heart disease and increase the risk of heart failure, myocardial infarction, sudden death and other conditions in patients. Patients with severe stenosis of coronary artery lumen have significantly reduced blood flow in the blood vessels, which is clinically known as coronary artery disease, and if patients are not treated in a timely manner, it will have a serious impact on their health. First of all, early coronary heart disease will lead to chest tightness, chest pain, shortness of breath and other symptoms, seriously affecting the patient’s daily life, and secondly, with the development of the patient’s condition, there will be arrhythmia, cardiogenic shock, fainting and other symptoms. At the same time, the patient’s heart is in ischemic state for a long time, which will cause cardiac function damage, leading to heart failure, myocardial infarction and so on. As the disease cannot be cured at present, although the patient’s condition is controlled after treatment, it will continue to progress, so the patient has a higher risk of sudden cardiac death and other serious conditions in the later stage. To summarize, severe stenosis of coronary artery lumen is a relatively serious cardiovascular disease, and it is recommended that patients seek medical treatment as soon as possible to improve the narrowing of blood vessels through stenting and other means to control the development of the disease.