If heartburn is caused by transient eating of spicy and irritating food, it can be cured after removing dietary factors; however, if it is caused by disease factors, such as chronic gastritis, acute gastritis, gastric and duodenal ulcers, etc., it can only be clinically relieved or cured after interventional treatments. 1. Chronic gastritis: When chronic gastritis is caused by long-term oral non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen, as well as long-term spicy and irritating foods, heartburn cannot be cured after it occurs. 2. Acute gastritis: If the gastric mucous membrane is damaged due to drinking a lot of alcohol, heartburn can also occur, and it needs to be relieved by fast inhibition of gastric acid and protection of the gastric mucous membrane, which usually cannot be cured by itself. 3. Gastric and duodenal ulcers: gastroduodenal ulcers can also be manifested as a burning sensation in the stomach, and this situation can not be self-healing. To summarize, heartburn can be cured after removing dietary factors if it is caused by transient eating of spicy and stimulating foods; if it is caused by disease factors, therapeutic interventions need to be carried out to deal with the different causes of heartburn, and only then can it be clinically relieved or cured. If the heartburn is caused by disease, it is necessary to address the different causes of heartburn to achieve clinical relief or cure.