Liver hypodense foci are lesions in the liver that are usually found to be below normal tissue density on ultrasound or x-ray, for example. Some of the hypodense foci in the liver are primary liver cancer, malignant liver metastases, cirrhotic carcinoma, hepatic adenoma, and liver abscess. Low-density foci in the liver do not mean malignant tumors. Some benign lesions also show low-density focal changes, while malignant tumors are often low-density foci. For some low-density foci that cannot be clearly identified as benign or malignant tumors, they can be identified by enhanced ultrasound, enhanced CT, enhanced MRI, and combined with tumor markers, such as methemoglobin and carcinoembryonic antigen.
If the examination reveals low-density foci in the liver, one must be alert to the possibility of liver malignancy and needs to refine relevant tests to clarify the etiology of the low-density foci and to differentiate and distinguish benign from malignant lesions. Since there is a great difference in the prognostic regression between benign and malignant lesions, different treatment options need to be chosen depending on the disease.