Painful and uncomfortable pressure on the thumb of the foot may be localized gout, or it may be nail infection, or purulent dactylitis, or other skeletal lesions, such as bone cysts, osteochondroma, etc. It is still necessary to go to the orthopedic department of the hospital in time to see a doctor, who will make a preliminary analysis with physical examination. If there is redness and swelling, the possibility of inflammatory diseases such as gout will be higher, and the determination of uric acid can be improved. If it is nail fungus, it is necessary to remove part of the nail and actively give antibiotics, such as cephalosporin, to treat it. If it is considered to be a bone lesion, you can improve the local X-ray examination to help determine the condition.