Whether or not you can take cold and anti-inflammatory medications together depends on which cold and flu medication you are going to take, but it is generally not recommended to take the two together to avoid increased medication risks. Most patients with colds may experience early symptoms such as nasal congestion, runny nose, cough, pharyngeal discomfort and other mild symptoms, while severe cases may experience systemic symptoms such as fever, chills, headache, fatigue, loss of appetite and so on. Cough suppressants, expectorants, antipyretics and antiallergics are often used symptomatically. Anti-inflammatory drugs usually refer to antibiotics, including penicillin, amoxicillin, levofloxacin, cefuroxime, moxifloxacin, etc. Before use, you need to choose sensitive antibiotics according to the type of infectious agent for treatment in order to have a better therapeutic effect. Drug interactions may occur when combining cold and anti-inflammatory medications, therefore, it is not recommended to take the two medications together. In addition, before using the medication, you should first clarify which kind of drug is suitable for you, if you can’t clarify, you need to consult your doctor and use the medication under the doctor’s guidance, and you should not blindly combine the medication on your own, so as to avoid serious effects.