In general, the normal value of fPSA/tPSA is >0.25. If fPSA/tPSA <0.15, it suggests that prostate cancer is more likely. PSA is a prostate-specific antigen found in the epithelial cells of the prostate ducts.About 80% of PSA in serum exists in bound form, called complex PSA (c-PSA), and about 20% exists in free form, called free fPSA. Normally tPSA should be <4ng/ml, fPSA should be <0.8ng/ml, and fPSA/tPSA should be >0.25. Elevated PSA is mainly seen in prostate cancer, but also in benign diseases of the prostate such as prostatic hyperplasia and prostatitis. Generally speaking, tPSA>10ng/ml suggests that there may be prostate cancer, but tPSA in 4~10ng/ml can be caused by prostate cancer or benign prostate disease. fPSA/tPSA is mainly used to identify benign and malignant prostate diseases when tPSA is 4~10ng/ml. fPSA/tPSA <0.15 suggests that prostate cancer is more likely to be present, while >0.15 suggests that benign prostate diseases are more likely. It is recommended that patients should take the reference values in the examination reports of local hospitals as the basis and compare the examination results to see if there are any abnormalities, and if there are any abnormalities, they should consult with specialists in time and follow the doctor’s instructions for further examination and treatment.