Dizziness when sitting up with l2 vertebral compression fracture may be caused by upright hypotension, otolithiasis, cervical spondylosis and other diseases. 1. Upright hypotension: Upright hypotension may be caused by insufficient blood volume, drugs, long-term bed rest and other factors. Symptoms are dizziness, vertigo, and narrowing of field of vision, etc. Patients with l2 vertebral compression fracture may experience dizziness when sitting or standing quickly. 2. Otolithiasis: The etiology of otolithiasis has not been clearly defined, and it may be caused by factors such as circulatory disorders of vertebral basilar artery and trauma. When the patient’s head position changes, vertigo, dizziness, nausea and other symptoms can suddenly appear, and the patient manifests dizziness when lying in bed and sitting up. 3. Cervical spondylosis: The causes of cervical spondylosis include chronic strain injury, high pillow, cervical degenerative disease, etc. Patients may experience cervical back pain, headache, and pain in the back of the neck. Patients can appear neck and back pain, dizziness, nausea, numbness of the limbs and other symptoms, manifested as dizziness when lying in bed and sitting up. There are many reasons why patients with l2 vertebral compression fracture become dizzy when lying down and sitting up, and it is recommended that patients find out the causes of the disease in a timely manner and target treatment and therapy.