Uric acid 400 μmol/L is not normal in female patients, while 400 μmol/L in male patients is still within the normal reference range. The normal range of blood uric acid is 89-357 μmol/L in adult women and 150-416 μmol/L in adult men. Therefore, a fasting blood uric acid test result of 400 μmol/L in female patients suggests that there is an increase in uric acid, while a fasting blood uric acid test result of 400 μmol/L in male patients is not yet higher than the upper limit of the normal reference range, which is a normal situation. Uric acid test value is higher than the upper limit of the normal reference range of male or female patients need to pay attention to low purine diet, avoid eating seafood, beans and soy products, animal offal and other high-purine foods, obese patients should be appropriate weight loss, if necessary, should be taken under the guidance of a physician to lower uric acid drugs to control uric acid. It is recommended that patients with uric acid 400μmol / L to the regular hospital endocrinology, rheumatology and immunology department for detailed consultation.