Anal dropping and ants sensation are considered to be related to hemorrhoids, sinusitis, perianal abscess, rectal prolapse, etc. 1. Hemorrhoids: the etiology is not yet completely clear, may be related to the theory of anal cushion displacement, varicose vein theory. In the early stage, there may not be any symptoms, with the development of bleeding, perianal itching, perianal pain, hemorrhoidal prolapse, perianal distension, etc., which may be manifested as anal dropping, ants feeling. 2. Sinusitis: mainly caused by bacterial infection, improper diet, fecal stimulation and other triggering factors. Patients mainly have the feeling of incomplete defecation, anal canal falling sensation, anal itching, etc., can also be manifested as anus falling, ants feeling. 3. Perianal abscess: Perianal abscess is mostly originated from anal crypt infection, but also can be secondary to trauma, Crohn’s disease. Patients mainly have persistent swelling and pain in the perianal area, especially in defecation, walking, aggravated. Some patients may also suffer from anxiety, difficulty in defecation, fatigue, fidgeting, etc. They may also suffer from anus dropping and ants sensation. 4. Rectal prolapse: Rectal prolapse can cause some patients to have anus falling, ants feeling, but also easy to be accompanied by mucus stool, constipation, urgency, anal sacrococcygeal distension, fecal incontinence, rectal bleeding, perianal skin itching or pain and other symptoms. The etiology of rectal prolapse has not been clarified and may be related to the doctrine of sliding hernia and intussusception. It is recommended that those who have anal dropping and ants sensation should seek medical examination in time in order to clarify the disease and then follow the doctor’s instructions for treatment, which will help to alleviate the uncomfortable symptoms.