Herpes pharyngitis is a common infectious disease in infants and children and is usually most severe on days 3-6. Herpes pharyngitis is an infectious disease caused by viral infections, mostly in infants and children, associated with coxsackie A16 and EV71 virus infections. The course of the disease is divided into three phases, including the incubation period, prodromal phase, and the onset of the disease. The incubation period is 1-2 days, and the patient has no symptoms; the prodromal period is day 2-3, and the patient has symptoms such as fever and blisters on the palate; the onset period is day 3-6, and the patient may have fever, oral ulcers, pain, drooling, refusal to eat, etc. The symptoms are most severe at this time, and symptomatic treatment is the main focus. The disease is self-limiting and usually heals in about 1 week. In conclusion, because herpes pharyngitis is highly contagious, patients should be isolated and the dishes they use should be disinfected to prevent cross-infection.