As we all know, the prevalence of hypertension in China continues to increase, with almost 1/3 of the adult population suffering from hypertension or having blood pressure above normal high values. This means that the number of people with hypertension in China is large, and the latest statistics show that the number of people with hypertension is close to or has exceeded 300 million. As long as the rise of blood pressure, it may damage our blood vessels, heart, brain, kidneys, retina and other multi-organ tissues. When hypertension is changed, it should be treated by lowering the blood pressure, to what level should it be lowered? Combined with the latest hypertension guidelines for detailed answers. First, the fundamental goal of lowering blood pressure and initiating treatment The fundamental goal of treating hypertension is to reduce the total risk of cardiac, cerebral and renal complications and death, and the benefit of lowering blood pressure comes mainly from the blood pressure reduction itself. Theoretically, if a hypertensive patient’s blood pressure remains above 140/90 mm Hg despite lifestyle improvements, antihypertensive drug therapy should be initiated along with interventions for correctable risk factors, target organ damage, and coexisting clinical conditions. In terms of the mode of BP lowering attainment, most hypertensive patients should have their BP lowered to target levels within 4 weeks or 12 weeks, depending on their condition, except in acute and subacute hypertension. In addition, intensive antihypertensive treatment strategies should be adopted to achieve maximum cardiovascular benefit when conditions permit. For elderly people aged 65-79 years, the first step should be to reduce to <150/90 mmHg, and if tolerated, further to <140/90 mmHg; for elderly people aged ≥80 years, the first step should be to reduce to <150/90 mmHg, and if tolerated, further to <150/90 mmHg. For patients with hypertension in pregnancy, blood pressure should be <150/100 mmHg; 4. For patients with cerebrovascular disease: <140/90 mmHg if the stroke patient is stable, and <180/110 mmHg for those with acute ischemic stroke and ready for thrombolysis; 5. For patients with coronary artery disease, BP should be <140/90 mmHg, or <130/80 mmHg if tolerated, and care should be taken not to lower DBP too low; 6. In patients with hypertension combined with heart failure, blood pressure should be controlled below 140/90 mmHg.