1.Knowledge of individualized lung cancer treatment in modern medicine
I have always held different views on the authoritative guidelines for individualized treatment of lung cancer, and I believe that the guidelines have many incorrect or need to be improved! I not only know individualized treatment from pathology and tumor molecular markers, but also talk about individualized treatment of lung cancer from 7 aspects, such as location of primary tumor lesion, tumor metastasis, tumor stage, previous treatment plan, and luckology.
The main regimens for the treatment of lung cancer are platinum-containing regimens, and platinum-containing regimens are mainly with paclitaxel, docetaxel, gemcitabine, vincristine, irinotecan, etoposide, vincristine, pemetrexed, etc. The combination of gemcitabine and paclitaxel has also been reported, and some of these drugs can be combined with erlotinib. How to combine these drugs most rationally and achieve the greatest efficacy is the focus of research in recent years. In response to the current status quo, I have taken the following aspects to integrate treatment individualization with satisfactory efficacy.
Before talking about treatment individualization, I classify the above drugs as hot and cold for the following recognition. The cold drugs are paclitaxel, vincristine, etoposide, and bevacizumab, and the hot drugs are gemcitabine, irinotecan, gefitinib, erlotinib, and pemetrexed. Docetaxel is not well classified yet. I recognize the classification of drug chills and fever mainly from 4 aspects.
(1) According to the site (primary and metastatic site), the drug is presumed to be hot, cold, dry and moist.
(2) Based on the type of pathology, the cold, heat, dryness and dampness of the drugs are inferred. Squamous carcinoma and small cell carcinoma are more common in smokers, and more of them are located near the lung gate and are fire, but small cell carcinoma is different from squamous carcinoma. In limited stage small cell lung cancer, EP is the golden solution, the classic solution, after repeated application of EP solution or extensive stage small cell lung cancer, IP solution has the advantage, why? Adenocarcinoma is mostly small peripheral lesions, commonly found in non-smoking patients and female patients, mostly cold; prone to pleural fluid and lymph node metastasis, the presence of pleural fluid is mostly Yang deficiency, lymph node metastasis is mostly phlegm and dampness, so adenocarcinoma is mostly cold and damp; pemetrexed is preferred for adenocarcinoma, pemetrexed is a hot drug.
(3) It is to recognize the cold, heat, dryness and dampness of drugs according to the side effects of drugs. People recognize the side effects of drugs mainly to avoid risks, but can people draw useful contents from the side effects. I think we can identify the Chinese medicine from the side effects, and it is easy to find out the cold, heat, dryness and dampness of the drugs, which is beneficial to the rational clinical application of drugs. For example, paclitaxel causes different degrees of joint and muscle pain, and only cold is most likely to cause pain, so paclitaxel is a cold drug; moreover, paclitaxel causes leukopenia, hypotension, bradycardia, anorexia, edema, etc., which is also a school of yin evidence, from which it can also be recognized as a cold drug. Cetuximab causes red rash all over the body, which is a hot class drug. Irinotecan causes dry mouth, dry and cracked hands and feet, which is dry in nature. Why? The 19 articles of the Nei Jing and Liu Wansu proposed that “all astringent and dry, dry and chapped, all belong to dryness”.
(4) According to bone marrow suppression. Recognize the hot and cold of drugs, from the speed of white blood cell damage, the damage is fast for cold drugs, slow for hot drugs, because Yang is easy to rise suddenly, Yin is difficult to become quickly. The red system is yin and the white system is yang. Hot drugs damage both yin and yang, while cold drugs only damage yang.
After understanding the cold, heat, dryness and dampness of drugs, we will focus on the individualized treatment of lung cancer
(1) Selection according to pathological type: In recent years, non-small cell lung cancer has been divided into squamous carcinoma and adenocarcinoma, and the drugs used are different from each other. According to the 2009 edition of NCCN guidelines, NP and GP regimens are effective for squamous carcinoma, while paclitaxel plus cisplatin, bevacizumab and pemetrexed plus cisplatin regimens are effective for adenocarcinoma, without talking about which pathological types TP regimens are effective for. In 2011, ASCO proposed that paclitaxel plus cisplatin plus bevacizumab has no therapeutic advantage, and that paclitaxel liposome is effective in squamous carcinoma, and paclitaxel liposome is effective in squamous carcinoma, and paclitaxel must be effective in squamous carcinoma. 2009 edition of the guideline is also inconsistent with this theory, that is, GP program is effective in squamous carcinoma. If so, why is it that the B2-07 study meta-analysis of 6671 patients showed that the first-line regimen containing Kenzyme significantly reduced the risk of disease progression by 14% in patients with advanced non-small cell lung cancer, while the first-line regimen containing paclitaxel significantly increased the risk of disease progression by 21%? How to explain? Chinese medicine believes that there are more Yang deficiency in advanced tumors, and paclitaxel is a cold drug, so cold drugs are used for cold disease, so paclitaxel is not effective for advanced non-small cell lung cancer and will promote disease progression, while gemcitabine is a hot drug, and hot drugs are naturally effective for cold disease.
(2) According to biomarker selection: Recently, it was found that the high rate of epidermal growth factor receptor (EGFR) mutation in lung adenocarcinoma is good for choosing gefitinib and erlotinib. 2009 at the 13th World Lung Cancer Congress Tony Mok et al. reported the effect of EGFR mutation on efficacy in the IPASS study, and there may be a dominant mutation among exon 19 and 21 mutations, and exon 19 exon mutation may be more effective against gefitinib. High expression level of thymidylate synthase (TS) in lung squamous carcinoma, an insulin-related protein with good insulin-like growth factor receptor (IGF1R) expression for squamous carcinoma was investigated. the higher the expression level of ERCC1, the lower the cisplatin resistance and the stronger the drug resistance. the higher the expression level of RRM1, the lower the sensitivity of gemcitabine and the stronger the drug resistance. the higher the mRNA expression level of BRCA1 The higher the mRNA expression level of BRCA1, the higher the sensitivity of paclitaxel or vincristine, the worse the prognosis of NSCLC patients and the worse the response to platinum-containing regimen chemotherapy. The detection of these indicators has important implications for the selection of drugs. It is interesting: BRCA1 is associated with two cold drugs, paclitaxel and vincristine, rather than with paclitaxel (cold drug) and gemcitabine (hot drug) or paclitaxel and irinotecan (hot drug), a result that supports my view and is very interesting! Cetuximab in combination with chemotherapy significantly prolongs survival in patients with advanced non-small cell lung cancer, and current data suggest that the benefit of cetuximab in combination with chemotherapy is not affected by KRARS or EGFR mutations. The expression of EGFR in selected human tumors is shown in the table below.
Expression of EGFR in selected human tumors
Colon cancer 25%-77%
Head and neck cancer 95-100%
Pancreatic cancer 30%-89%
Non-small cell lung cancer 40%-80%
Renal cell carcinoma 50%-90%
Breast cancer 14%-91%
Ovarian cancer 35%-70%
Glioma 40-63%
Bladder cancer 31%-48%
What does this table tell us? This table illustrates that the Chinese medicine has the same origin and treatment of different diseases; it also illustrates that head and neck and glioma have a single pathological mechanism; while intestinal cancer, breast cancer and pancreatic cancer have a more complex pathological mechanism. k-ras and EGFR mutations do not exist at the same time, and the scope of treatment of gefitinib, erlotinib and sunitinib is not the same, this scope is mainly about the different scope of cold, heat, dryness and dampness in Chinese medicine, which is not recognized by western medicine at present.
It is believed that tumor angiogenesis depends on circulating endothelial cells, i.e. endothelial cells shed from the vessel wall or endothelial cells mobilized from bone marrow to the peripheral circulation to differentiate into aCECs, which in turn form tumor blood vessels, therefore, it is important to judge tumor neovascularization and vascular targeting based on endothelial cells. Therefore, it may be important to judge the efficacy of tumor neovascularization and vascular targeting therapy based on endothelial cells.
(3) Selection according to the site of primary lesion: I have talked about the correlation between tumor site and pathology earlier, and many patients have unclear pathology from the beginning to the end because of many factors. In fact, according to the location of the lesion, chemotherapy regimens or targeted therapy drugs can be selected. Those with primary foci located in the hilum with mediastinal lymph node metastasis are mostly small cell lung cancer, so EP regimens should be selected, and CPT-11/DDP regimens should be used after drug resistance (EP regimens are colder, so CPT-11/DDP regimens with heat will be effective after drug resistance). TP and NP regimens; those with lymph node enlargement in the mediastinum near the periphery are mostly adenocarcinoma, so choose the regimen for adenocarcinoma; those with scattered nodal shadow in the lung and small mediastinal lymph nodes are mostly alveolar carcinoma, which are mostly in people who are easily irritated with temper and have phlegm and fire in Chinese medicine, so the treatment effect is better than adenocarcinoma. However, alveolar carcinoma located near the pleura is better treated as adenocarcinoma. It should be noted here that although squamous carcinoma and adenocarcinoma are both non-small cell carcinoma and different from small cell carcinoma, the main cause of squamous carcinoma and small cell carcinoma is smoking and they are both central lung carcinoma, so there are many similarities in treatment. This can be easily explained in traditional medicine. Squamous carcinoma and small cell carcinoma are both phlegm-heat, only the degree is different, but adenocarcinoma is different, it is cold and damp. In Japan, it was reported that irinotecan plus cisplatin regimen has an advantage over EP regimen in the treatment of small cell lung cancer, but the same conclusion was not reached in Europe. The EP regimen is cold and the irinotecan plus cisplatin regimen is hot. For example, the effect of Irinotecan plus cisplatin regimen is better than EP regimen in SCLC patients with pleural fluid and brain metastasis.
Pemetrexed plus cisplatin regimen is effective in treating adenocarcinoma and pleural mesothelioma, why? It is located near the periphery and is cold and wet, so the application should make the treatment of pleural mesothelioma with GP and IP regimen effective even if the economic condition is poor. However, in clinical practice, it is found that pleural mesothelioma with a wide range of lesions and also lesions in the mediastinum are effective with sunitinib.
(4) Selection according to metastases: In clinical practice, it is found that chemotherapy is effective for metastatic tumors in some sites and ineffective for metastatic tumors in others. Generally speaking, lymph node metastasis is cold and damp, brain metastasis is phlegm-heat with wind, liver metastasis is blood deficiency, osteolytic metastasis is blood stasis with heat, adrenal metastasis is dirty cold, pleural and pericardial metastasis is Yang deficiency, and those with multiple metastases mostly see Yang deficiency and lack of vital energy. Therefore, when treating tumors with metastases, we should not only focus on the primary foci, but also take into account the metastases. Sometimes the site and manifestation of metastases are more meaningful for choosing chemotherapy regimens. In the clinic, we found that gefitinib is effective in treating lung cancer with combined pleural fluid, water and pericardial effusion, and sometimes effective in treating brain metastasis of lung adenocarcinoma, but rarely effective in bone metastasis, which is not difficult to explain with the above theory. Similarly erlotinib is 27% effective in treating patients with lung squamous carcinoma, which 27% are those patients in the end, I guess mainly patients with lung squamous carcinoma of near peripheral type, appearing pleural fluid, pericardial effusion and brain metastasis, I don’t know if it makes sense.
(5) According to staging selection: the B2-07 study meta-analysis of 6671 patients yielded the result that patients with advanced non-small cell lung cancer had a significantly reduced risk of disease progression of up to 14% with a first-line regimen containing Jianzhi; while a first-line regimen containing paclitaxel significantly increased the risk of disease progression by up to 21%, an example of staging in relation to chemotherapy drugs. The more advanced the tumor stage, the weaker the yang energy, the more hot drugs should be chosen instead of cold drugs. Paclitaxel is a cold drug, so paclitaxel is not effective for advanced non-small cell lung cancer and will promote disease progression. Gemcitabine is a hot drug, and hot drugs are naturally effective against cold diseases.
In Japan, it was reported that irinotecan plus cisplatin regimen has an advantage over EP regimen for small cell lung cancer, but the same conclusion could not be reached in Europe. In fact, irinotecan plus cisplatin regimen is more effective after EP resistance, and it is also more effective in advanced disease with irinotecan plus cisplatin regimen. So the effect is better with the irinotecan plus cisplatin regimen.
These are the types of pathology that you cannot choose chemotherapy regimens from.
In order to have more accurate staging, it is necessary to understand the easy metastatic sites of lung cancer, which are easy to metastasize in lung portal mediastinal lymph nodes, pleura, brain, bone, liver, adrenal gland, etc. The necessary tests that should be performed are physical examination, blood routine, blood biochemistry, tumor markers (CEA, NSE, CY-211, CA153, etc.), chest X-ray, chest and upper abdomen CT, lung function, brain MRI, bone scan, fiberoptic trachea
(6) According to the previous treatment plan selection: foreign countries have observed the application of gefitinib followed by chemotherapy with Jianze, paclitaxel, and Tysodi regimen, paclitaxel has the highest efficiency of 27%. People have this experience, the application of gefitinib resistance and then paclitaxel, sunitinib effective, why? Gefitinib is a big hot drug, after applying for a period of time will turn the body hot, this is you use paclitaxel, sunitinib this cold drug will be effective, if you choose irinotecan and other hot drug effect will not be good. Therefore, after we clarify the cold and heat of chemotherapy drugs, and at the same time observe the drugs used in front of us, and choose the drug with the opposite of cold and heat after the emergence of drug resistance, naturally there will still be efficacy, even if the drug has been used before.
(7) Selection according to the conclusion of luckology: I have repeatedly discussed luckology many times before.
To sum up, the selection of chemotherapy drugs and targeted therapy drugs can never be decided by simple pathology, and the above seven factors must be considered to improve the therapeutic efficacy.
According to my clinical observation, the cold drug power paclitaxel and sunitinib is greater than vincristine and etoposide, and the hot drug pemetrexed is better than other chemotherapy drugs; erlotinib has a wider therapeutic range than gefitinib, and the efficacy of erlotinib tablets is currently considered to be unaffected by EGFR mutations.
In addition, the shape and location of metastases in the lung can help determine the origin.
Of course, individualized treatment of lung cancer still faces many problems, such as whether to choose cisplatin for all chemotherapy, whether the current drug dose is reasonable, how to combine targeted and chemotherapy, which of the above 7 factors is the most important and how to judge them, and so on.
I think that when the primary tumor is slowly increasing and no new lesions appear, the anti-cancer power is not enough to treat in the right direction with similar stronger anti-tumor drugs. Part of the drugs; the primary foci rapidly increase, change to another type of program, to contain anti-cancer drugs to clear heat; tumor extensive metastasis, must be extremely supportive, targeted drugs (according to the last program), to protect the body.
What needs to be emphasized here is that the current knowledge of Western medicine is not completely correct. A dean of Harvard Medical School once said that after ten years it was found that 50% of our current knowledge is wrong, but unfortunately we do not know which is wrong. Then how to screen the right and wrong? Using TCM theory, we TCM can help them analyze what is wrong, the key is awareness and thinking.
When you read my previous information, 2011 ASCO Lung Cancer Update you can interpret it well, such as CP combined with vascular blockers did not improve the efficacy; CP combined with motesanib could not significantly improve OS in patients with non-squamous NSCLC; JMDEI study retrospective analysis showed that pemetrexed was significantly better than docetaxel in second-line treatment of advanced non-squamous NSCLC; anti-vascular drugs may may weaken the efficacy of EGFR-TKI in EGFR mutants; oral angiogenesis inhibitors in progressive non-squamous NSCLC did not prolong OS; pemetrexed combined with erlotinib second-line therapy significantly improved PFS and OS in NSCLC patients.
2. Knowledge of lung cancer diagnosis and treatment in Chinese medicine
I have my own independent ideas about the identification of lung cancer. I dare not keep it a secret, but I would like to share it with the public as a way to draw inspiration.
(1) Etiology and pathogenesis
It is not a simple deficiency of lung qi, or deficiency of both lung and spleen, but a deficiency of the spleen, lung and kidney. The deficiency of lung, spleen and kidney is the root cause, while phlegm, blood stasis, ligament blockage and cancer toxicity are the symptoms.
(2) Key points of identification and treatment
Shortness of breath is a manifestation of deficiency of spleen and lung; shortness of breath, salty throat and salty phlegm are the main symptoms of kidney deficiency. The lung is the storage device of phlegm, so regardless of whether there is phlegm or not, the phlegm should be eliminated. Expel blood stasis and promote water. Anti-tumor, use gecko, burnt dried toad, etc. to fight cancer and disperse nodes. To treat lung cancer, we should support the righteousness, dispel phlegm and eliminate stasis at the same time.
Here we have to emphasize that many Chinese medicine treatment of lung cancer is not only benefit qi and nourish yin, phlegm and anti-cancer, benefit qi and nourish yin is not only raw pulse, mai men dong soup, etc., phlegm is not only zhebeimu, gua basket, half summer, etc., anti-cancer is not only snake tongue grass, gold buckwheat, centipede and other drugs. Without tumors, these drugs sometimes partly barely cope, once with tumors are often helpless. Famous Chinese medicine Guo Xiwu senior said lung disease is not outside the gas knot, phlegm and water, a word to break the organ. Water knot scape Dajiao diarrhea lung soup, Xiao Qinglong, Ling Gui agent can be treated, the effect is obvious; but the clinical feeling of phlegm is always weak, the effect is not obvious, need to use sea floating stone, green hazy stone, bile south star. Anti-cancer need to make a heavy punch, the choice of toad skin, gecko and other products, non-white flowered snake’s tongue, gold buckwheat can be. Fu Zheng with 30 grams of Astragalus, Ginseng 15 acrylic is not enough, and the use of both and Astragalus need more than 50 grams, not knowing that the spleen and stomach for the source of phlegm, the spleen and stomach health can break the root of phlegm, tumors such as no food and grass supply to die. For patients with chronic bronchitis, it is difficult to eliminate phlegm by simply replenishing the spleen and lung, such as adding kidney with Shu Di and Angelica, phlegm will be eliminated. As the ancient saying goes, “phlegm originates from the kidneys; phlegm that moves the dampness is mainly in the spleen; phlegm at the end of the drink is also stored in the lungs”. For lung cancer, we must consider the problem of spleen deficiency and kidney deficiency.
(3) Individualized treatment
At present, modern medicine talks about individualized treatment, but in fact, ancestral medicine emphasizes individualized treatment the most, and individualized treatment is reflected in the content of evidence-based treatment.
a. Add and subtract according to the pathology: Generally speaking, adenocarcinoma is mostly cold and damp, so products that warm the yang and transform dampness should be used more often, such as sliced pith, dry ginger, barley and mulberry skin. Squamous carcinoma and small cell carcinoma are mostly phlegm-heat and yin deficiency, and small cell carcinoma is more severe than squamous carcinoma, and should be given to golden buckwheat, fishy grass, guajia, lily, maitong, etc. Pulmonary alveolar carcinoma with qi and blood cleansing products, such as green peel, orange peel, heliotrope, curcuma, golden buckwheat, etc.
b. Add and subtract according to the primary site: if there is no clinical pathology or pathology is unknown, those with foci in the periphery are treated as adenocarcinoma, those near the hilum are treated as squamous carcinoma or small cell carcinoma, and those with scattered diffuse are treated as alveolar carcinoma.
c. Add or subtract according to the metastases: Generally, TCM doctors think that metastasis is the deficiency of positive qi, and it is enough to supplement positive qi, while some think that it is the flourishing of evil, and it is necessary to strengthen the elimination of evil. To look at it from another perspective, can a pincer do the work of a tiler, a planker, an electrician, etc., admittedly not, then can one Chinese medicine fight all lung cancer metastases? There is already a large deficiency of vital energy, and the vital energy should be greatly tonified.
d. Add and subtract according to the luck science: according to the luck science of birth, we can deduce which aspects of the patient are weak and know in advance which organs are prone to metastasis.
e. Add or subtract according to the metastasis site after treatment: if the primary foci increase and no new foci appear, then we should consider that the general direction of treatment is correct, but the power of anti-tumor treatment is insufficient, and we should increase the power of anti-tumor; if the primary foci increase and new foci appear at the same time, then we should consider that the anti-tumor treatment is insufficient, and at the same time we should consider that the positive energy of lung is insufficient, then we should not only fight against tumor but also support the positive energy, so that we can stabilize the tumor. Only then can the tumor be stabilized. If the primary foci are enlarged and metastasized at multiple sites at the same time, and the metastasis is very rapid, then it is not only a problem of insufficient treatment, but also a possible deficiency of positive qi.
f. Add and subtract according to symptoms: Patients with lung cancer may have various symptoms, so they can be added and subtracted according to various symptoms, and the treatment of difficult symptoms of lung cancer will be specifically discussed later.
(4) Basic prescription
Raw Astragalus membranaceus 50g, Zhi Mu 20g, Sheng Ma 3g, Calcined Sea Fushi (firstly) 50g, Bai Ying 20g, Lily 30g, Shu Di 30g, Angelica Sinensis 20g, Chen Pi 10g, Qing Qing Xian Xia 15g, Fu Ling 15g, Bile Nan Xing 15g, Di Long 15g, Shou Gong 30g, Jiao Shan Zha 30g, Dry Ginger 10g, Hsio Xin 3g, Zhan Dong Hua 12g.
Add and subtract according to pathology: squamous carcinoma and small cell carcinoma add 30g of golden buckwheat, 3g of antelope horn powder (divided into punch), 10g of saponaria, 10g of burnt dried toad; adenocarcinoma add 15g of lobelia, 10g of epiphyllum (first down), 10g of cinnamon stick, 10g of Sichuan pepper eye.
If there is blood in the sputum, add 10g of Bupleurum and 30g of Xianhecao; if the fever is high fever with solid pulse, give Angong Niuhuang Wan orally; if the fever is low fever, add 15g of Ground Bark, 10g of Yin Chaihu, 20g of Artemisia annua (later), 10g of Dan Pi. For itching in the lung, add 30g of Radix Polygoni and 30g of Radix Bupleuri; for itchy throat and cough, add 30g of Plantago lanceolata and 10g of Silkworm; for constipation, add 60g of Atractylodes macrocephala and 6g of Rhubarb in wine; for insomnia, add 10g of Cicadelle and 30g of Rhizoma Polygonatum; for cough when lying down, add acidophilus; for dry cough, add 30g of Fructus spp.
Special medication: coughing up blood in the cavity of lung cancer can be caused by excessive central necrosis of squamous cancer lesions and after bevacizumab treatment. It may be difficult for many people to understand how to stop the bleeding when Acacia Bark is a drug for relieving depression and detoxification. In fact, we know the drug from the textbook, many very effective drug function in the textbook selection process was artificially omitted, very unfortunate. The ancient book of Haplopodium has a very good expectorant and hemostatic effect, the recovery period of pulmonary carbuncle (lung abscess) is often taken with a single decoction of Haplopodium, named Huang Faint Soup, as an effective drug for the late repair of pulmonary carbuncle.
Cracked hands and feet: Cracked hands and feet can occur after using Gefitinib. Use 15g of Comfrey, 30g of Radix et Rhizoma, 20g of Radix et Rhizoma, 10g of Bupleurum, 20g of Lily, 10g of Mulberry leaf, one dose of water decoction for external washing daily.
Red rash: Many targeted therapeutic drugs can cause rash, some very serious, part of the long in the face affects the beauty, available Fu Ling, forsythia, honeysuckle, bitter ginseng, Xia Gu Cao Cao, Dan Pi and other drugs, water decoction, with gauze dipped in medicine, compress on the patient. It can be applied several times a day.
Radiation pneumonia: a common side effect of radiotherapy for lung cancer, esophageal cancer and breast cancer, modern medicine has no good effect on this disease, Chinese medicine is more effective in treating it. If it is extremely stubborn and conventional medicine is ineffective, use Yinhua 20g, Ziziphiopogon 12g, Dangdong Hua 12g, Hujian 15g, Radix Platycodon 15g, Guaguaguajou 12g, Fructus septica 20g, Fritillaria 20g, Bupleurum 10g, Almond 10g, Mulberry Peel 12g, Rutabaga 12g, Bupleurum 10g, Peach kernel 10g, Dongguaren 10g, Job’s tear 12g, Huangjing 10g, Bupleurum 10g, Sea clam powder 15g, licorice 6g, Zhi Mu 15g, Huang Bai 12g, Zhen Zhen Zi 10g, one dose daily, coughing blood and then add Xian He Cao 12g, water decoction, this is a deceased famous doctor in Tangshan to treat bronchial dilatation formula, bronchial dilatation has many similarities with radioactive pneumonia, pulmonary fibrosis, so it is used to treat radioactive pneumonia, pulmonary fibrosis with satisfactory results, you may use it. Ligustrum lucidum 10g, Fructus Lycii 10g, Fritillaria caryophyllus 20g, pills, 6g per pill, 2 times a day. The bronchial dilatation treatment and consolidation formula is a gift from Director Qi Preservation of Tangshan Bureau of Statistics, and we would like to express our gratitude on behalf of the patients.
The lung cancer advanced bed-ridden coughing sputum weak, sputum, which is very easy to lung infection to promote the death of patients, Western medicine is often helpless in this case, Chinese medicine with ginger 10, red dates 10, decoction of water for tea, most can quickly get rid of phlegm, probable spleen and stomach is the source of phlegm, ginger warm stomach to drink, red dates to strengthen the spleen, spleen healthy drink phlegm since elimination, although the drug is simple but the effect is very fast, should not be underestimated.
Tumor patients are averse to greasy after chemotherapy: some tumor patients are averse to greasy after chemotherapy, some are averse to greasy for life, even cannot smell the smell of fried food, and are nauseous when they see oil. According to my clinical observation for many years, chewing ginger or adding dried ginger or ginger in soup can effectively treat greasiness during chemotherapy or after greasiness.
(5) Other therapies
Some patients with lung cancer have nodules around lung Yu and Ting gas point, which can be meaningfully treated by blood pricking and cupping moxibustion for the disappearance of lung cancer tumor. Acupuncture points such as Zhonggui, Qihai and Guangyuan can be re-moxibuted.