Indomethacin is a non-steroidal anti-inflammatory drug that treats gout and is the drug of choice for the treatment of gouty arthritis, providing rapid relief from the red, swollen, hot and painful symptoms of gouty arthritis. In addition, drugs such as ibuprofen and diclofenac are all commonly used NSAIDs. During an acute attack of gout, patients can choose colchicine for treatment. Colchicine is a specific drug for the treatment of gouty arthritis, and 90% of patients are able to relieve their symptoms 48 hours after taking the drug. After the symptoms are relieved, the dosage can be gradually reduced until the drug is discontinued. Glucocorticoids are an option for treating acute attacks of gout if the patient has contraindications to the use of nonsteroidal anti-inflammatory drugs such as colchicine or indomethacin. Patients with gout can be treated with uric acid-lowering therapy after 2 weeks of symptomatic relief. The uric acid-lowering drugs commonly used in clinical practice include drugs that promote uric acid excretion, such as benzbromarone and probenecid, as well as drugs that directly inhibit uric acid production, such as allopurinol. Sodium bicarbonate, as an alkalinizing drug, can alkalinize the urine and reduce the deposition of urate in the urinary tract, thus controlling the attack of gouty nephropathy, so it is also commonly used in the treatment of gout and hyperuricemia. In addition, for patients with high uric acid and gout, they should limit or control the consumption of high-purine foods, so as to prevent gout attacks.