There is no cure for ankylosing spondylitis in female patients even after the age of 40. Ankylosing spondylitis is an immune system disease that cannot be completely cured under the current level of medical technology. Therefore, regardless of gender or age, once you have ankylosing spondylitis, there is no way to completely cure it, and only different treatments can be given at different times of the day, with the ultimate goal of preserving the function of the large joints as much as possible, and minimizing the destruction of joint function as a result of this disease. The ultimate goal of treatment is to preserve as much joint function as possible and minimize the damage to joint function caused by the disease. During acute exacerbations, the disease should be treated systematically with medication, and during non-acute exacerbations, the joints should be strengthened with functional exercises.