Sleeping will cough, coughing wake up first need to clarify the diagnosis, such as cough variant asthma, heart failure, gastroesophageal reflux disease, etc., need to be relieved through the treatment of the cause such as medication. 1. Cough variant asthma: due to airway hyperresponsiveness, genetic factors and environmental factors, cough variant asthma often coughs at night or early in the morning, and needs to be treated with glucocorticosteroids combined with adrenergic agonists, such as budesonide formoterol powdered inhalation, leukotriene receptor antagonists, such as montelukast, etc., under the guidance of a doctor. 2. Heart failure: due to the increase of the return blood volume when lying down, leading to the aggravation of heart failure and the increase of pulmonary stagnation, which leads to the emergence of nocturnal coughing and sedentary respiration, etc., it is necessary to improve the symptoms of heart failure by applying furosemide, spironolactone, digitalis and other drugs. 3. Gastroesophageal reflux disease (GERD): Due to lying down, acid reflux is aggravated, resulting in coughing and waking up at night. Should develop good habits, avoid eating before bedtime, eat less and more meals, etc. At the same time, serious cases need to apply drugs, such as omeprazole, mosapride, etc. to improve the symptoms. If necessary, anti-reflux surgery such as laparoscopic fundoplication can be performed. There are other reasons that can cause sleeping cough, coughing and other symptoms, such as postnasal drip syndrome, etc. If the symptoms are not relieved or aggravated, it is recommended to consult a doctor in time to find out the cause and standardize the treatment under the guidance of the doctor.