Creatinine 600mg/dl indicates renal failure, first of all, we should distinguish whether it is acute renal failure or chronic renal failure. If it is acute renal failure, you can give short-term hemodialysis treatment, nutritional support, hormones and immunosuppressants to treat if necessary. If it is chronic renal failure, you can give detoxification drugs such as urinary toxicity Qing granules, Haikun kidney hi capsules, and if necessary, hemodialysis treatment. When creatinine is found to be significantly elevated, you should not jump to conclusions, such as the need for long-term hemodialysis treatment, etc. The first thing to do is to clarify whether the acute renal failure or chronic renal failure. Because acute renal failure has the possibility of full recovery, while chronic renal failure does not have the possibility of full recovery. Acute renal failure is mostly acute tubular necrosis type, acute progressive nephritis and acute interstitial nephritis are also more common in clinical practice. Among them, acute tubular necrosis type of acute renal failure is mainly symptomatic support treatment, in the creatinine 600mg/dl need to give short-term hemodialysis treatment, in addition to give adequate nutritional support, at the same time to control blood pressure. For acute nephritis and acute interstitial nephritis, hormones and immunosuppressants can be given along with hemodialysis to treat the condition. In the case of chronic renal failure, detoxification drugs can be taken at a creatinine level of 600 mg/dl to observe the effect, and if the effect is poor, long-term hemodialysis treatment is required.