Simply staying up late will not be creatinine elevation, long-term staying up late can cause high blood pressure, elevated blood lipids, can cause kidney damage, kidney damage can cause blood creatinine elevation. Therefore, it is recommended to develop the habit of waking up early and going to bed early. It is recommended to go to bed before 11 p.m. to avoid causing hypertension and elevated blood lipids. Once high blood pressure and elevated blood lipids appear, it must actively control blood pressure and blood lipids so as not to cause kidney damage. The emergence of renal, but also creatinine elevation, the current medical science has no specific drug treatment. The main thing is to delay the progress of renal function, avoid the application of nephrotoxic drugs, protect the residual renal function, control blood pressure, reduce proteinuria. At present, the medical creatinine-lowering drugs are medicinal charcoal tablets, Chinese patent medicines are urethane clear particles sea, Kun kidney Xi capsule, Chinese medicine colon dialysis can also lower creatinine, once there are dialysis indications, it is recommended to carry out dialysis to maintain life.