The 24-hour urine protein quantification is mainly done by collecting all the urine of a patient for 24 hours and measuring the protein content in it mainly by a laboratory method to diagnose diseases of the urinary system. This test is also known as 24-hour urine protein excretion rate measurement, which starts from the first urine excretion in the morning of the same day and continues until the same time the next day. The total amount of urine protein in 24 hours. In normal people, there is usually less than 150 mg of urine protein in the urine. If the dose exceeds the normal dose, the underlying cause should be analyzed in conjunction with clinical symptoms. Generally in strenuous exercise, fever, and mental stress can also lead to temporary elevation of urine protein, which can usually be relieved after rest. Many diseases, glomerular disease, tubular disease, multiple myeloma, urinary tract inflammation, stones, tumors, and other diseases can cause damage to the filtration pore size and charge barrier of the renal filtration membrane, resulting in the filtration of protein from the original urine and a significant increase in 24-hour urine protein quantification. 24-hour urine protein measurement is a quantitative diagnostic method for diagnosing kidney disease. If a significant increase is found, it is usually a serious kidney disease.