Overall, the evolution of liver cancer can be divided into three processes: early stage, middle stage and terminal stage. 1. Early stage: the tumor is small, usually with a diameter of 1~2cm, and the tumor envelope is intact, without local invasion and outward dissemination via bloodstream metastasis, patients may have no uncomfortable symptoms, and most of the lesions are found during physical examination. If the patient’s liver is of good texture, surgical resection can be performed for treatment. If the patient has severe cirrhosis and cannot be surgically resected, radiofrequency ablation and microwave intervention can be performed to achieve complete necrosis of the tumor. If the patient has more serious cirrhosis and poor coagulation function and cannot undergo radiofrequency ablation, liver transplantation can be carried out to achieve the purpose of eliminating the tumor and treating cirrhosis at the same time. 2. Intermediate stage: no distant metastasis may have occurred, but the tumor size may be larger and the number of tumors has increased, at this time, interventional therapy can play a therapeutic role. In addition, embolization agent or chemotherapeutic drug can be used to kill the tumor, which can also play a certain therapeutic role. 3. End stage: the tumor has metastasized, and the patient may have ascites, jaundice, poor liver function and other manifestations, in which case the treatment effect may be poorer. Patients can adopt comprehensive treatment, interventional therapy, targeted drug therapy, immunotherapy and so on according to the specific conditions of patients, which can help prolong the survival time of patients.