How long does the rabies vaccine take to be effective

The rabies vaccination requires five injections, which take a total of almost a month before and after the vaccination. The mechanism of action is to allow the body’s immune system to produce neutralizing antibodies that can fight rabies. Neutralizing antibodies usually appear between the 7th and 14th day of vaccination and become positive, at which point the immunity is established. If the hepatitis B vaccine was given after the bite and there is still no rabies attack on the 7th-14th day of the vaccination, the rabies vaccine is likely to have taken effect. If you have not had an attack after the rabies vaccine, you can basically rest assured. Rabies vaccination is best administered within 24 hours of the bite to produce the appropriate antibodies within the next 1-2 weeks, which is generally much less than the incubation period for a rabies attack. If the first vaccination is delayed by a week or even a month, it is also recommended that the injection be given at this time, because the period after the injection is likely to allow one to produce antibodies, and it is only after the production of antibodies that immunity to rabies is obtained.