Pain in front of the calf bone may be caused by calf fracture, osteoporosis, myofasciitis, bone tumor, trauma and other reasons. 1. Calf fracture: Fracture may be caused by direct impact of heavy objects, long-term strain, heavy laborers, etc. The patient will have pain in the calf, which will be aggravated by moving the fracture or activities, and accompanied by local swelling, ecchymosis and other symptoms. 2. Osteoporosis: Osteoporosis is mostly caused by low physical activity, long-term smoking, alcoholism, lack of vitamin D, etc. Patients will have diffuse bone pain locally, and the pain symptoms will be aggravated after a long time of walking or interacting with each other, and some of the patients will also have the symptom of activity limitation. 3. Myofasciitis: Myofasciitis may be caused by trauma, excessive activities, cold and other reasons, the affected area will appear muscle pain, mostly persistent dull pain, soreness and swelling pain, in the cold or the morning when the pain symptoms will be aggravated. 4. Bone tumor: Bone tumor is usually caused by gene mutation, when the bone tumor presses on the surrounding bone, it will stimulate the periosteum to cause local edema, thus causing pain in front of the calf bone. 5. Trauma: The common trauma caused by bumping on the calf will often cause pain in front of the calf bone. There are many reasons for the pain in front of the calf bone, and the pain may occur after climbing mountains or stairs, so you should go to the hospital in time for medical treatment and active diagnosis and treatment, so as not to delay the condition.