The first step to confirm the diagnosis of leukoplakia is to go to a dermatologist at a regular hospital. In clinical practice, dermatologists can identify and diagnose through personal experience or can use instrumentation. At present, you can borrow the Wood’s lamp examination, vitiligo can generally be shown as blue-white. Secondly, it can also be examined by skin CT, which can observe the pigmentation under the skin. These two examinations, which are not yet clearly diagnosed, can be performed by histopathology of the skin, which is the gold standard for diagnosing the disease. Most of the leukoplakia will be clearly diagnosed by histopathology, so after the appearance of leukoplakia, you should go to a regular hospital for diagnosis and treatment as soon as possible. The prognosis is generally better, so do not blindly treat.