Antihypertensive medications affecting sexual function can be considered to be discontinued/changed, e.g., to valsartan, enalapril, felodipine, etc. Among the five major types of antihypertensive drugs recommended for use in hypertension treatment guidelines, beta-blockers (metoprolol/propranolol) and diuretics (hydrochlorothiazide) often cause hypogonadism, affecting erectile function in men. In this case, angiotensin II receptor antagonists (valsartan, irbesartan), angiotensin-converting enzyme inhibitors (captopril, enalapril), and calcium channel blockers (nifedipine, felodipine) can be replaced, and these medications can avoid hypogonadism caused by lowering blood pressure. The specific use of drugs should follow the guidance of clinicians.