The checklist above is the checklist of a 65-year-old woman with normal liver function and ultrasound. After being referred to our hospital by others, we wanted to ask what was going on. After reading all the tests of this patient, carefully asking about the medical history and physical examination, we again issued three checklists, ultrasound, liver function and a liver antigen profile. The results revealed a positive anti-soluble liver antigen antibody (anti-SLA), clearly informing that she had autoimmune hepatitis (AIH), which is type I. So what is autoimmune hepatitis? The immune system is one of the most complex systems in our body. Unlike other systems in our body that can be perceived, such as the digestive system and cardiovascular system, this system is one of the most indispensable systems in our body and is the most effective weapon to defend against pathogenic invasion. Like the army of a country, it mainly resists foreign invasion. However, this system is sometimes hostile and sometimes some organs of the body are damaged and are damaged by the immune system as foreign molecules. Autoimmune hepatitis is an inflammation of the liver parenchyma mediated by an autoimmune response against hepatocytes, characterized by positive serum autoantibodies, hyperimmunoglobulin G and/or gamma-globulinemia, and the presence of interface hepatitis in the liver histology, which if left untreated can often lead to cirrhosis and liver failure. the clinical manifestations of AIH are varied and generally present as chronic, insidious onset, but can also present as acute attacks The clinical manifestations of AIH are diverse and generally present as chronic, insidious onset, but can also present as acute attacks, even causing acute liver failure. AIH has become an important component of non-viral liver disease and is receiving more and more attention from gastroenterologists and hepatologists in China. The clinical manifestations of AIH are diverse, and most AIH patients have an insidious onset and generally present with chronic liver disease. The most common symptoms include drowsiness, fatigue, and general malaise. Physical examination may reveal signs such as hepatomegaly, splenomegaly, ascites, and occasionally peripheral edema. AIH can be classified into two types according to autoantibodies: type 1 AIH if positive for anti-nuclear antibody (ANA) and/or anti-smooth muscle antibody (ASMA), or anti-soluble liver antigen antibody (anti-SLA); type 2 AIH if positive for anti-liver-kidney microsomal antibody-1 (anti-LKM-1) and/or anti-liver cytosolic antigen-1 (anti-LC-1). Anti-SLA is highly specific for the diagnosis of AIH. Corticosteroids were chosen for treatment. In this patient, I chose observation for the time being and regular review due to normal liver function.