The treatment methods for advanced gastric cancer include surgery, chemotherapy, targeted drug therapy, radiotherapy, Chinese medicine, etc. Since patients with advanced gastric cancer will have cancer metastasis, they may not be able to remove all cancer cells in one surgery, or their physical condition is too weak to bear the trauma brought by surgery. However, if surgery can be performed, surgery should be preferred and postoperative treatment should be combined with other treatments to prevent recurrence. If surgery is not possible, patients should choose chemotherapy or radiotherapy treatment, together with targeted drug therapy, such as Apatinib, ramolutumab, trastuzumab and other drugs, or use traditional Chinese medicine treatment, which can control the spread of cancer cells, improve patients’ quality of life and prolong their survival. During the treatment period, patients should pay attention to diet, supplement nutrition, improve body resistance and immunity, and enhance physical fitness, so that patients can better resist the disease. At the same time, they should adjust their emotions in general, maintain a good state of mind and avoid having too much stress, which is conducive to improving the disease.