Among human bones, skull is considered to be relatively hard, but it is hard to resist the heavy blows from external forces, such as falling objects, traffic accidents, etc. Many people have their skull damaged because of these reasons. After skull defect, the intracranial tissues will be threatened by the outside world, which will easily lead to many health problems, so patients must pay great attention to it, and it is very necessary to go to the hospital for skull repair surgery in time. Of course, the choice of material is also very important when choosing skull repair surgery. Currently we apply a new polymer material, namely polyether ether ketone PEEK material. the clinical application of PEEK material is a good solution to problems such as titanium mesh leakage. Based on the biology of polymer materials, PEEK materials have good mechanical properties, ease of plasticity, chemical stability and biocompatibility, can withstand high-temperature steam and irradiation sterilization, and radioactive permeability and MRI scans do not produce artifacts, less dense, lighter weight implants are more comfortable and do not conduct heat. Current patients with a modicum of medical knowledge are choosing PEEK materials for skull repair. This is because, in terms of current clinical cases, not a single case of suspected complications has been identified. Although we cannot say with certainty that PEEK is perfect, the current medical and clinical analysis shows that PEEK is the best choice for cranial bone repair.