The probability of conversion of hepatitis B virus is generally related to the type of hepatitis B and whether it is properly treated, and the probability of conversion is not high. 1. Ineffective treatment: If the patient does not receive treatment, or the treatment is ineffective, the probability of conversion is extremely low, which may lead to the deterioration of the condition, causing cirrhosis, or even liver cancer. 2. Hepatitis B type: the chances of hepatitis B virus turning negative are related to the target, the chances of HBV-DNA turning negative are relatively high; e antigen turning negative, i.e., major triple Yang to minor triple Yang is relatively high; if it belongs to the surface antigen of hepatitis B turning negative, that is to say, the clinical cure, generally not too high, because the hepatitis B virus can not be cleared, and it is only possible to curb the replication of the virus through antiviral treatment. Hepatitis B virus is difficult to remove, it is recommended that after diagnosis, patients need to actively seek treatment to avoid affecting their health.