Commonly used anti-inflammatory drugs in anorectal department include penicillin, metronidazole or norfloxacin. 1. Penicillin: Penicillin has better bacteriostatic and bactericidal effects on staphylococcal infections caused by anal and intestinal inflammation; it can generally be used as a common medication for the treatment of anal and intestinal infections. 2. Metronidazole: Metronidazole has a better therapeutic effect on anaerobic bacteria, and less drug resistance, usually used in combination with other anti-inflammatory drugs to achieve a better therapeutic purpose. 3. Norfloxacin: quinolone drugs, E. coli has a good bactericidal effect, in addition to Norfloxacin also belongs to the broad-spectrum antimicrobial drugs; and the side effects are relatively small, not easy to produce resistance, is the use of more widely used in the treatment of inflammatory diseases of the anus and intestines drugs. The above anti-inflammatory drugs are recommended to be taken under the guidance of a doctor, and should not be taken on their own to avoid delays.