Unresectable pancreatic cancer mainly refers to tumors that are in the local progressive stage or have distant metastases. Depending on whether the tumor is in a locally progressive stage or has distant metastasis and the general condition of the patient, different adjuvant treatment options are adopted. In addition, for patients with severe complications, palliative surgery is feasible to relieve symptoms. Other palliative treatments Pancreatic destruction caused by the tumor and surgical removal of pancreatic tissue can lead to pancreatic insufficiency, and pancreatic enzyme replacement therapy and endocrine replacement therapy are recommended for symptomatic patients. Patients with pancreatic cancer are at a significantly higher risk of developing venous thromboembolic disease. For patients who develop venous thromboembolism, anticoagulation with low-molecular heparin, such as dalteparin sodium, is recommended.