Urticaria is an allergic disease, mostly due to allergies caused by excessive consumption of allogeneic proteins, including beef and mutton, seafood, as well as chicken, duck, goose and dog meat, bird’s nest and shark’s fin. Methylprednisolone can play an anti-allergic and immunosuppressive role and can be divided into oral methylprednisolone tablet dosage forms and also injectable dosage forms of methylprednisolone sodium succinate for sedation. In clinical treatment, if the area of urticaria is more extensive, itching is more intense, accompanied by dyspnea, dizziness, nausea, diarrhea, abdominal pain and other conditions occur, it is necessary to order methylprednisolone injection or oral methylprednisolone tablets to strengthen the anti-allergy treatment, together with the antihistamine drug fexofenadine hydrochloride tablets taken orally.