Amoxicillin should not be poured directly on the wound. In the clinic if the wound pus infection, its common treatment is the use of iodophor disinfection, local use of hydrogen peroxide rinse pus wound, at the same time remove inactivation of necrotic tissue, with saline rinse clean, again iodophor disinfection, the local use of izacrine bandage wounds, and at the same time oral amoxicillin or intramuscular or even intravenous injection of penicillin antibiotic drugs. Amoxicillin can not be used directly on the wound for two main reasons: first, in the clinic to avoid antibiotic drugs used directly on the wound, so as not to produce drug resistance; second, due to amoxicillin as a penicillin antibiotic, the sensitive bacteria are mainly gram-positive cocci, including Staphylococcus aureus, and its main mechanism to kill Staphylococcus aureus is to play the role of blood, and on the surface of the body against Staphylococcus aureus, but not to kill Staphylococcus aureus, but also to kill the bacteria. The main mechanism of killing Staphylococcus aureus is to play a role in the bloodstream, and the killing effect of Staphylococcus aureus on the body surface is limited, so amoxicillin should not be directly spread on the wound.