Generalized aches and pains after high fever require a combination of aggressive treatment of the primary illness, temperature control, and general care. 1. Treatment of primary disease: actively search for the causes of fever and generalized pain, improve blood analysis to determine whether the fever is infectious or non-infectious, and improve relevant examinations according to whether there are other accompanying symptoms. Actively treat the original cause of fever, such as cold, pneumonia, enteritis and other diseases. When the cause of fever is relieved and the body temperature is effectively controlled, the systemic symptoms will also be relieved. 2. Temperature control: if fever with generalized pain is obvious, physical cooling can be considered first, applying fever-reducing patches, ice caps, or warm water baths; if the effect of physical cooling is not obvious, and the temperature is high, such as more than 38.5 degrees Celsius, non-steroidal antipyretics can be used to control the body temperature, such as ibuprofen or acetaminophen. 3. General care: timely replenishment of body fluids, such as infusion rehydration. Fever will lead to a large loss of body fluids, further aggravating the clinical symptoms of generalized aches and pains. Patients should pay attention to rest, ensure sufficient sleep, drink plenty of warm boiled water, eat a light diet, eat more vegetables and fruits as appropriate to promote metabolism, promote the metabolism of lactic acid, accelerate heat dissipation and detoxification; massage the sore parts to accelerate local blood circulation, so as to achieve the purpose of relieving muscle aches and pains.