Mosapride cannot be taken together with lactulose, Mosapride should be taken before meals, lactulose should be taken once at breakfast, taking at the same time may affect the absorption of the drug. The main ingredient of mosapride is mosapride citrate, which is a digestive tract prokinetic agent, and the common preparations are tablets and capsules. Lactulose is an ammonia-lowering and laxative agent, and common preparations are oral liquids. Mosapride is mainly used in functional dyspepsia with early satiety, epigastric bloating, heartburn, nausea, vomiting, epigastric pain and other GI symptoms. Its adverse reactions include dry mouth, diarrhea, abdominal pain, lethargy, dizziness, etc. Contraindications are those with gastrointestinal bleeding, intestinal obstruction or perforation. Note that it should be discontinued if there is no change in symptoms after 2 weeks of administration. Lactulose is used for the treatment and prevention of hepatic coma or precomatose state, and is also used in the treatment of constipation. Its adverse effect is that electrolyte disorders may occur due to diarrhea when taken in high doses over a long period of time, note that it should be used with caution in patients with diabetes mellitus. Mosapride and Lactulose can not be taken together, Mosapride should be taken before meals, Lactulose should be taken at breakfast at one time, the drug should be applied correctly in order to avoid affecting its absorption and utilization. Mosapride and Lactulose should be taken under the guidance of a physician, and should not be used on its own to avoid adverse consequences.