Case sharing: The patient, 33 years old, found a left vulvar swelling for 1 year, about 3*2cm in size at that time, no pain and discomfort, the swelling gradually increased in size, and was considered “vestibular gland cyst” twice in the local hospital for incision and drainage, both recurred within 1 month after surgery, and increased in size compared with the preoperative period, no obvious conscious symptoms, now the swelling is about 4*5cm in size. Now the mass is about 4*5cm in size, and was admitted to the hospital as “vestibular gland cyst”. Examination: a cystic mass, about 4*5cm in size, with little tension, no tenderness, no fluctuating sensation, multi-cystic in shape, with palpable striated structures, vaginal patency, smooth cervix, anterior uterine body, normal size, no obvious abnormality in bilateral adnexal area. Diagnosis: vulvar tumor. The largest cavity was about 3*1cm in size and the smallest cavity was about 1*1cm in size, with clear borders, no infiltration around, and a fiber-like envelope on the surface. The cavity was filled with hemostatic sponge and drainage was left in place. On the 7th postoperative day, the vulvar incision healed well without obvious swelling, and a hard node with a diameter of about 1 cm was palpated at the base of the perineum (corresponding to the lowest end of the surgical cavity), without pressure pain or exudation. A follow-up examination 1 month after surgery showed that the incision at the perineum was healing well, and the hard node at the bottom was reduced to about 0.5 cm, without pressure pain. Postoperative pathology: vulvar angiomyofibroblastoma. On microscopic examination, the tumor cells were spindle-shaped, fat spindle-shaped, round or ovoid, and clustered around a large number of thin-walled vessels in a bundle or nest-like distribution, with alternating areas of abundant cells and areas of fewer cells, and a background of mucus and slender collagen fibers. (Figure 1 and 2) Figure 1 (HEx100) Figure 2 (HEx40) Discussion: 1. Vulvar myxofibroblastoma is a rare benign mesenchymal tumor of the vulva, first reported by Fletcher et al. in 1992, and less than 300 cases have been reported in the literature at home and abroad. It occurs mostly in the vulva of young and middle-aged women, especially in the labia majora, and some cases are located in the vagina and vulva, and a few cases can also occur in the perineum, groin, scrotum and spermatic cord of men. 2, pathological diagnosis: the diagnosis of the disease is based on postoperative pathology, the general morphology: clear perimeter, some cases are covered with a layer of fibrous pseudo-envelope, ranging from 0.5 to 14 cm in diameter, mostly less than 5 cm, the cut surface is grayish white or pink, soft texture, some areas are mucus-like. The typical histopathological features are a loose edematous interstitium rich in small thin-walled blood vessels and cell-rich and cell-sparse areas composed of alternating, unequal proportions of tumor cells, with fat spindle-shaped cells in the cell-rich areas and slender spindle or star-shaped cells in the cell-sparse areas. The tumor cells are diffusely and strongly positive for vi-mentin and desmin, with focal expression of actin, MSA and CD34. 3. Differential diagnosis: AMF is most easily confused with aggressive angiomucinous tumor. The two are similar in terms of age of predilection, location, histological morphology and immunophenotype, but AAM is locally aggressive, not easily resected completely, and has a high recurrence rate, so differentiation from AMF is essential. The differentiation points are: AMF is relatively superficial, the tumor volume is small usually less than 5 cm, and the tumor border is clear or has a fibrous pseudo-envelope, while AAM is deeper, the tumor volume is larger usually more than 5 cm, and the tumor border is unclear; AMF cells are alternately distributed in cell-rich and cell-sparse areas, and the tumor cells are spindle-shaped, fat spindle-shaped, round or ovoid, containing varying amounts of collagen with glassy degeneration, while AAM cells are stellate and stellate. In contrast, AAM tumor cells are stellate or shuttle-shaped uniformly distributed in extensive mucus-like degenerative interstitium, with positive mucus Ossian blue staining and no or sparse intercellular collagen; AMF tumors are rich in small to medium-sized thin-walled dilated vessels, mostly capillary type, while AAM vessels are of varying thickness, mostly thick-walled small vessels with collagen degeneration of the canal wall. 4. Prognosis: AFM is a benign tumor of the vulva, which can be cured by complete excision of the local tumor and generally does not recur, and it has been reported that the tumor has no recurrence for 19 months after simple lesion excision [4]. In this case, the perineal incision healed well at the follow-up of 1 month after surgery, and there was a hard node with a diameter of 0.5 cm at the place of hemostatic gauze, without redness or swelling and without pressure pain, which was considered to be related to the absorption of the hemostatic gauze, without exudation and without recurrence. Only one case of highly malignant sarcoma-like transformation was reported in the literature. 5. Treatment experience: AFM is a rare benign tumor of the vulva, which is easily misdiagnosed as vestibular gland cyst before surgery, and is often found intraoperatively and confirmed by postoperative pathology. In this case, the author found that multiple clockwork-like structures could be palpated in the cyst, which was different from the common vestibular gland cyst, so he chose combined lumbar and rigid anesthesia, and chose to leave hemostatic gauze and place drainage because of the deep trauma during surgery and the difficulty of hemostasis and suturing. The review discusses that the treatment of traumatic bleeding can also choose to leave a negative pressure drainage device, using negative pressure to close the cavity can also stop bleeding, and can reduce the chance of hard node formation.