Uric acid 250μmol/L is within the normal range, at this time there are still gouty attacks, consider due to the uric acid lowering speed is too fast. Gout patients in the process of drug treatment, if the beginning of the application of a larger dose of drugs, can make the blood uric acid content decreased rapidly, limbs, joint cavity of the urate crystals can be dissolved into the blood again, the formation of local urate concentration is too high, stimulate the immune system, induced inflammatory reaction, resulting in severe pain. However, the appearance of the symptom indicates that the disease is getting better. It is recommended that in the treatment of gout, small doses of uric acid-lowering drugs should be applied, and the amount should be gradually increased after the body has tolerated it; anti-inflammatory and analgesic drugs can be used prophylactically if necessary, and a low-purine diet should be adopted on a daily basis to limit the intake of alcohol and increase the amount of water consumed. If gout treatment during the obvious discomfort symptoms, it is recommended to go to the hospital to follow the doctor’s instructions for treatment, regular review of renal function and other indicators to monitor the change of uric acid, in order to adjust the treatment in a timely manner.