Rotavirus infections are most severe around day 2-5, and occur most often in November-December each year and in January-February of the following year. The main manifestation of rotavirus infection is diarrhea in the form of loose watery or egg-like stools, accompanied by fever and vomiting, which can last for 2-3 days, and diarrhea can occur up to 10-20 times a day. The patient’s condition is most serious around 2-5 days, during which the body loses a lot of water due to diarrhea, so it is easy to develop dehydration, acidosis, electrolyte disorders and even convulsions. There is no specific drug for rotavirus infection, only symptomatic supportive treatment, and the whole course of the disease may last half a month to one month. In addition, the detoxification in the feces of most patients can last for about 10 days. In conclusion, after rotavirus infection, patients should pay attention to hydration, can feed appropriate amount of baking soda, refined salt glucose water, and also should control the diet, patients with severe vomiting need to fast for 6-12 hours.