Lipid-regulating drugs is a general term for a large group of drugs, mainly including statins, fibrates, niacin, bile acid chelators and so on. The following is a brief introduction of their respective characteristics and usage. Statins are the first choice of lipid regulators in clinical practice, mainly for patients with elevated total cholesterol and LDL cholesterol. The commonly used ones are Rosuvastatin, Atorvastatin, Simvastatin, Fluvastatin and so on. Doctors will individualize treatment by selecting statins with different lipid-modifying intensities and doses according to each patient’s cardiovascular risk stratification. The main adverse effects are hepatotoxicity and muscle adverse reactions. However, the overall incidence is not high, and it is safe and reliable as long as it is used under the guidance of doctors. 2, Betablockers Betablockers are suitable for hypertriglyceridemia or mixed lipid population with mainly elevated triglycerides, including clofibrate, benzofibrate, fenofibrate, etc.. Adverse reactions include indigestion, elevated transaminases, and occasionally allergic skin reactions. 3, niacin Niacin and its derivatives are essentially B vitamins, when the dosage exceeds the dose when it is used as a vitamin, there is a significant lipid-regulating effect. It is mainly used for patients with hypertriglyceridemia and mixed dyslipidemia, especially when high-density lipoprotein cholesterol (HDL-C) is reduced or when triglycerides are increased. Commonly used are niacin extended-release tablets and acipimox. The main adverse effects include gastrointestinal symptoms such as nausea and vomiting. 4.Ezetimibe is a selective cholesterol absorption inhibitor, which is suitable for hypercholesterolemia or mixed dyslipidemia. For patients with familial hypercholesterolemia, the preferred treatment is statin combined with cholesterol absorption inhibitor. Adverse effects of this drug include a small amount of gastrointestinal flatulence and diarrhea, which generally do not require special treatment. 5, bile acid chelators Bile acid chelators are a class of drugs that inhibit the reabsorption of cholesterol-rich bile acids, thereby promoting cholesterol excretion, mainly koleleneamine, koletipol and so on. Common adverse reactions include gastrointestinal reactions, such as nausea, abdominal distension, constipation, etc. 6, in addition to fish oil class such as ω-3 series polyunsaturated fatty acids, etc., but there is not much research evidence, so it is not widely confirmed. In conclusion, it is recommended to use lipid-regulating drugs under the guidance of cardiologists in regular hospitals.