Commonly used analgesic and sedative drugs, mainly include the following: 1, analgesic drugs: opioids, non-opioid central analgesic drugs and non-steroidal anti-inflammatory analgesic drugs. Opioids are more commonly used, such as morphine, fentanyl, remifentanil and sufentanil, etc. 2, sedative drugs: benzodiazepine sedative drugs and central alpha 2 agonists. Benzodiazepines are mainly imipramine and diazepam. Central α2 agonists are mainly dexmedetomidine injection.