Rabies is an acute infectious disease caused by rabies virus, which is common to humans and animals, mostly seen in dogs, wolves, cats and other carnivores, and people are mostly infected by the bite of diseased animals. The clinical manifestation is mostly characterized by fear of water and wind, pharyngeal muscle spasms, progressive paralysis, etc., and is also known as hydrophobia because of the prominent symptoms of hydrophobia. The morbidity and mortality rate of this disease is nearly 100%, and patients generally die of respiratory or circulatory failure within 3-6 days, so the emergency treatment after being bitten is particularly important. First of all, early treatment of the wound is an important step to avoid rabies virus infection, with 20% soapy water to fully clean the wound, and then constantly rinse and wipe, deeper wounds still need to use the catheter to reach in, soapy water for continuous perfusion cleaning, in order to remove the dog saliva. After cleaning, the immune serum is then injected into the wound base. Special attention should be paid to the need for skin testing before using the immune serum, and a negative skin test should be used before injection. Secondly, preventive vaccination is required. For patients with primary exposure (contact, feeding animals, or intact and undamaged skin licked and touched by animals), preventive measures are generally not required, but careful observation should be made to see if the skin is indeed unbroken, and do not be paranoid about leaving traces of tooth marks on the skin, as there may be skin damage that is difficult to detect with the naked eye, and rabies virus may invade the body along with the tooth marks, so the bitten area needs to be immediately The bite site should be disinfected immediately by thoroughly washing the site with soap and water, applying iodine, and then administering rabies vaccine throughout. For patients with secondary exposure (light bites or minor abrasions or scratches on bare skin by animals, but no bleeding), vaccination should be given immediately. For patients with tertiary exposure (one or more skin bites or scratches or mucous membranes contaminated with saliva, broken skin where the animal licked, or exposure associated with bats), rabies immunoglobulin is required in addition to immediate vaccination. Vero cellular electric vaccination: 0, 3, 7, 14, 30 days after bite prophylaxis, 0, 7, 21 days without bite prophylaxis. 1ml each time, with a booster on the 90th day, and the injection site is appropriate for the deltoid muscle of the upper arm; children less than 2 years old can be injected on the outer thigh. Rabies immunoglobulin includes human immunoglobulin and equine immunoglobulin. Rabies immune globulin neutralizes rabies virus and should be used immediately after the bite. Rabies is an acute infectious disease with a very high death rate and a lack of effective treatment, so do not take any chances after being bitten by an animal and treat it urgently to effectively avoid rabies virus infection.