Herpes zoster blisters usually disappear spontaneously in about 20 days without being picked, and herpes zoster has a tendency to heal itself. The blisters of shingles are only one of its external manifestations, and the patient may also have localized skin erythema, papules, etc., along with the appearance of nerve damage, which manifests as neuralgia. Although the rash may subside on its own and the nerve damage will be repaired to some extent, the possibility of remaining neuralgia is greatly increased in elderly people who are not given regular antiviral and nerve-nourishing medications. Therefore, if a diagnosis of shingles is confirmed, early and regular treatment is still recommended, especially in the elderly. In addition, patients should also be aware that if they need to pick the blisters open according to their condition, they should be treated in a hospital and should not do it themselves to avoid aggravating the condition by causing secondary bacterial infections.