Many outpatients request glucosamine sulfate for the treatment of osteoarthritis, bone spur formation, and osteophytes.
The reason for this is that the old American Guidelines for the Treatment of Osteoarthritis of the Joints had previously recommended the use of glucosamine sulfate for patients with osteoarthritis, and some articles have reported that it has some therapeutic benefit. However, studies in recent years with large samples have found that glucosamine sulfate is not significantly effective in the treatment of osteoarthritis, nor does it have an effect on cartilage repair, and its effect is only equivalent to that of a placebo. Therefore, the latest guidelines no longer recommend the use of glucosamine sulfate for the treatment of osteoarthritis.
It is recommended that medical practitioners and patients adjust their treatment strategies to avoid unnecessary waste of medical resources and ineffective treatment. The following new treatment guidelines are attached.
Guidelines for the treatment of osteoarthritis of the knee (other than knee arthroplasty) in the United States
I This guideline recommends effective methods for the treatment of knee OA
1. Patients with a body mass index (weight/height squared) of more than 25 should lose at least 5% of their body weight
2. Aerobic low-intensity adaptive exercise
3. Use acetaminophen (no more than 4 g/d) or non-steroidal anti-inflammatory drugs for pain relief. In addition, topical NSAIDs, or oral gastroprotective agents and COX-2 inhibitors can be used for patients at high risk of gastrointestinal distress.
4.For short-term pain relief, intra-articular glucocorticoid injections can be used.
5.Arthroscopic surgery can be performed in case of meniscal injury or free body
6. Patellar support band for short term pain relief
This guideline does not recommend the following treatment measures for knee OA
1. Joint irrigation
2. Glucosamine or (and) chondroitin sulfate (hydrochloride)
3. orthopedic foot brace
4. Arthroscopic irrigation in the absence of free body or meniscus damage as an inconclusive outcome
III Treatment of unspecified treatment measures
1.Intra-articular sodium hyaluronate injection for mild and moderate OA
2.Support
3.Acupuncture