The normal range of ALT is 5~40U/L, and the normal range of GGT is 4~38U/L. The clinical reasons for the elevation of both ALT and GGT are mainly due to hepatocellular injuries caused by various factors, such as physiological factors and pathological factors such as viral hepatitis. 1. Physiological factors: first of all, staying up late can lead to the elevation of these two indicators. 2. Pathological factors: when liver cells are damaged by various pathological factors such as fatty liver, alcoholic hepatitis, viral hepatitis and drug poisoning, liver cells will rupture, and these two substances will be released into the bloodstream, resulting in the elevation of ALT and GGT in the bloodstream, so high ALT and GGT should be taken seriously. Therefore, high ALT and GGT should be taken seriously. If the patient’s ALT and GGT are obviously high, he/she should go to the hospital in time to have a review and find out the corresponding reasons to prevent delaying his/her condition.