Mesalazine is an aminosalicylic acid preparation, which can be combined with antidiarrheal drugs such as montelukast, gastrointestinal antispasmodics such as atropine, gastric stimulants such as domperidone, and immunosuppressants such as cyclophosphamide to treat chronic colitis. 1. antidiarrheal drugs: chronic colitis increased stools, can choose montelukast and other antidiarrheal drugs, help repair the mucosa of the digestive tract, reduce intestinal peristalsis, so as to achieve the purpose of stopping diarrhea. 2. Gastrointestinal antispasmodics: anticholinergic drugs such as atropine, scopolamine, etc. can eliminate spasmodic pain; calcium antagonists such as nifedipine, pivotal ammonium bromide, etc. can relieve gastrointestinal spasm. 3. Gastric stimulants: such as domperidone, itopride, etc. can enhance gastric motility and reduce indigestion and other symptoms. 4. Immunosuppressants: such as cyclophosphamide, etc., which are suitable for hormone dependence and maintenance therapy after hormone-induced remission. Mesalazine can be combined with many other medications to treat chronic colitis, such as antibiotics like ciprofloxacin. All of the above medications should be taken under medical supervision and should not be used without authorization.