Creatinine is a product of muscle metabolism and is an ideal indicator of kidney function because it is filtered by the glomerulus and not reabsorbed by the tubules, so it is not absorbed into the blood. Therefore, when evaluating whether creatinine is elevated, it is important to combine the reference value of the local hospital. Elevated creatinine indicates renal failure, but renal failure does not necessarily mean the development of uremia, because renal failure is also divided into acute and chronic, acute cases can be fully recovered in many cases, while only chronic cases can gradually develop into uremia. Therefore, if elevated creatinine is found, we must actively search for the cause and stop it, so that it can be completely restored to normal.