The normal value of serum β2 microglobulin is about 1~2mg/L. This index can be used to evaluate renal function and test for certain diseases, and abnormalities of this index need to be consulted in time. Serum β2 microglobulin is a kind of globulin produced by lymphocytes, platelets and other nucleated cells, which is widely found in plasma, urine, cerebrospinal fluid, saliva and so on. Normal human serum β2 microglobulin concentration is very low, and in the proximal tubule almost all reabsorbed, the adult serum concentration of the substance is about 1 ~ 2mg / L, different laboratories may have some differences. Serum β2 microglobulin can be used to evaluate glomerular function. When glomerular filtration is impaired, β2 microglobulin is retained in the blood and its concentration will increase. Meanwhile, in the occurrence of IgG nephropathy, malignant tumors, as well as a variety of inflammatory diseases such as hepatitis, rheumatoid arthritis, etc. can lead to an increase in the production of β2 microglobulin. It is recommended to go to the hospital in time to avoid any delay in the occurrence of the above diseases or abnormalities in serum β2 microglobulin.