Tenofovir antiviral for two years, the viral load is still 300 indicates that the treatment is effective, the body is weakly positive for the virus, there is no need to be overly anxious, regular review can be. The normal value of hepatitis B virus DNA measurement is less than 1.0X10^3IU/mL, which indicates that the patient’s body is weakly positive for the virus, and no treatment is needed, but should be reviewed regularly. If there is no obvious abnormality in the morphology and structure of the liver in the hepatitis B virus DNA, liver function tests and abdominal ultrasound, and the patient does not have uncomfortable symptoms, it means that the virus replication in the patient’s body is not active. In this case, patients can follow the doctor’s instructions to regularly review the measurement of hepatitis B virus DNA, liver function and abdominal ultrasound and other related examinations, and closely monitor the patient’s condition. If uncomfortable symptoms occur, you should consult a doctor as soon as possible for examination to identify the cause of the disease and then deal with it under the guidance of the doctor.