Increased testosterone is usually seen in testicular mesenchymal stromal cell tumor, adrenal gland diseases, tumors or medication causes, etc., and should go to the hospital in time to find out the cause of the disease. 1. Testicular mesenchymal stromal cell tumor is a kind of testicular tumor, which can present with testicular swelling, accompanied by increased serum testosterone level, which needs to be further diagnosed by testicular imaging examination. 2. Tumor of adrenal gland or hyperplasia of adrenal cortex will lead to increased secretion of hormones by adrenal gland, which will cause increased serum testosterone level, and imaging examination of adrenal gland is needed to confirm the diagnosis. 3. Tumors in testis and pituitary gland can produce too much androgen, which will lead to the increase of testosterone level in the body, and the patient should be actively treated for the primary disease. 4. If patients use testosterone injections or gonadotropin injections, they may have increased testosterone values, which are mostly related to the use of drugs, and can be recovered after stopping the drugs. If the testosterone is increased after examination, the patient can be re-examined to rule out the error, and if necessary, consult the doctor in the regular hospital to clarify the cause of the disease and follow the doctor’s instructions for treatment.