Tonify the spleen and intestines pill and tonify the middle-earth pill are two kinds of Chinese patent medicines with different ingredients, and their efficacy and indications are also different. 1. Different ingredients: the main ingredients of tonifying the spleen and intestines pills are Codonopsis, Atractylodes macrocephala, Cinnamon, Ginger, Fenghuang, and Mucuna pruriens. 2. Different efficacy: tonifying the spleen and intestines pill has the effect of benefiting qi and nourishing blood (replenishing the body’s qi and blood), warming yang to move qi, astringent intestinal diarrhea, focusing on astringency and diarrhea; and tonifying qi pill has the effect of tonifying qi and lifting yang to lift the sunken organs, focusing on lifting yang to stop diarrhea (lifting the yang to treat diarrhea). 3. Different indications: Tonifying the Spleen and Benefiting the Intestine Pill is mainly used for the treatment of diarrhea due to spleen deficiency (diarrhea caused by weak function of the spleen), and is used for diarrhea caused by deficiency of the spleen and stagnation of the qi, which can be seen as abdominal distension and pain, intestinal sounding and diarrhea, and mucus and blood in stools; and chronic colitis, ulcerative colitis, and allergic colitis can be seen in the above mentioned indications. Tonifying Zhong Yi Qi Pill is suitable for diarrhea and prolapse caused by weakness of spleen and stomach, sinking of middle qi (deficiency of spleen and stomach qi, with the appearance of falling of internal organs), which is specifically manifested as low food intake and abdominal distension, tiredness and fatigue, loose stools (thin and unshaped stools), prolonged diarrhea, falling of anus or uterine prolapse, and so on. Patients should take Tonifying the Spleen and Intestine Pills and Tonifying the Middle Jiao Qi Pills under the guidance of a professional Chinese medicine practitioner, and should not blindly self-medicate to avoid ineffective treatment and delay of the condition.