What people usually call hormone drugs refers to glucocorticoids, which mainly include the following side effects: i. It can make the body trunk fat increase while the limb fat does not increase, that is, centripetal obesity. Second, it can cause osteoporosis and femoral head necrosis. Third, the body’s resistance decreases, blood sugar rises, electrolyte disorders and peptic ulcers. Fourth, it leads to increase in blood pressure. In conclusion, hormone is an effective therapy for most patients, and it is very effective in controlling the development of the disease in the short term especially in acute activities, but the side effects of long-term high dose application are great, and hormone therapy is not used as much as possible.