Can patients with advanced kidney cancer have surgery? Most people think that kidney tumor cannot be operated when it has metastasized, but in fact it does not mean that it cannot be operated, and surgery at this time is often for palliative purpose. Palliative or subtractive nephrectomy means that even if the tumor cells have spread to other parts of the body, the treatment effect can still be improved by removing the primary lesion and the patient still needs to receive systemic treatment. The removal of primary lesion is very important for the treatment of metastatic kidney cancer: 1. it can reduce the damage of tumor to the body and possibly improve the systemic treatment effect on metastatic tumor; 2. remove the source of tumor; 3. reduce the damage of tumor secreting ground hormone to human body; but for different patients, we need to consider the possible risks brought by surgery and post-operative rehabilitation, if the kidney cancer is huge, poor physical condition If the kidney cancer is huge and the physical condition is poor, surgery is not recommended. The most suitable candidates for tumor reduction surgery are those who do not have other serious diseases, are in good general condition, the kidney can be safely removed and most of the tumor load is located in the kidney. Can surgical resection be performed on metastases? Metastatic kidney cancer is a systemic disease and resection of metastases is usually not considered, but only under special circumstances, such as few metastases (one or a few), small lesions and metastatic lesions are within the area where surgery can be performed. Over time, metastases may also be found at other sites in most patients postoperatively.